Molecular Hydrogen for Athletes: Studies

The body of an athlete is a finely-tuned engine, and utilizing the right fuel is absolutely essential. Molecular hydrogen infuses every cell in the body with the tools to dramatically boost the body’s ability to augment every attribute necessary for maximizing your performance in basketball including strength, explosiveness, endurance, focus, coordination, range of motion, recovery, injury prevention, and much more. But hydrogen isn't just for elite athletes. Anyone looking to support an active lifestyle will find amazing benefits from H2.

The body of an athlete is a finely-tuned engine, and utilizing the right fuel is absolutely essential. Molecular hydrogen infuses every cell in the body with the tools to dramatically boost the body’s ability to augment every attribute necessary for maximizing your performance in basketball including strength, explosiveness, endurance, focus, coordination, range of motion, recovery, injury prevention, and much more. But hydrogen isn't just for elite athletes. Anyone looking to support an active lifestyle will find amazing benefits from H2.

Drinking hydrogen water enhances endurance and relieves psychometric fatigue

"Endurance and fatigue were significantly improved in the H2 group as judged by maximal oxygen consumption and Borg's scale, respectively. Taken together, drinking H2 water just before exercise exhibited anti-fatigue and endurance effects."

 

Mikami, T., Tano, K., Lee, H., Lee, H., Park, J., Ohta, F., … Ohta, S. (2019). Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study. Canadian Journal of Physiology and Pharmacology, 97(9), 857–862. doi: 10.1139/cjpp-2019-0059

Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes

“Although acute exercise resulted in an increase in blood lactate levels in the subjects given placebo water, oral intake of hydrogen water prevented an elevation of blood lactate during heavy exercise. Peak torque of placebo water significantly decreased during maximal isokinetic knee extension, suggesting muscle fatigue, but peak torque of hydrogen water didn’t decrease at early phase. Proper and adequate hydration is helpful for elite athletes to achieve the best performance. Hydrogen water can easily replace regular drinking water on a routine basis and would potentially prevent adverse effects associated with heavy exercise. In conclusion, our preliminary data demonstrated that consumption of hydrogen water reduced blood lactate levels and improved muscle fatigue after acute exercise. Drinking hydrogen water would be a novel and effective fluid hydration strategy for athletes.”

 

Aoki, K., Nakao, A., Adachi, T., Matsui, Y., & Miyakawa, S. (2012). Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Medical Gas Research, 2(12), 1-6. doi: 10.1186/2045-9912-2-12

 

 

Effects of hydrogen rich water on prolonged intermittent exercise

 

“In the PLA group, PPO in absolute values decreased significantly at the 8th and 9th of 10 sprints and in relative values, PPO, decrease significantly at 6th, 8th and 9th of 10 sprints (by mean: -12±5%, p<0.006), while it remained unchanged in HRW group. Two weeks of HRW intake may help to maintain PPO in repetitive sprints to exhaustion over 30 minutes.”

 

Ponte, A. D., Giovanelli, N., Nigris, D., & Lazzer, S. (n.d.). Effects of hydrogen rich water on prolonged intermittent exercise. The Journal of sports medicine and physical fitness, 57(6). doi: 10.23736/S0022-4707.17.06883-9



Molecular hydrogen affected post-exercise recovery in judo athletes

“Molecular hydrogen significantly blunted lactate response during recovery period as compared to the placebo (7.23 ± 1.95 vs 9.22 ± 1.51 mmol/L; p = 0.011). Furthermore, a trend has been found for decreased post-exercise heart rate in group supplemented with H2 (p = 0.111). Hydrogen-rich water appears to be an appropriate strategy to positively affect post-exercise lactates in judo athletes.”

Drid, P., Stojanovic, M. D., Trivic, T., & Ostojic, S. M. (2016). Molecular hydrogen affected post-exercise recovery in judo athletes. Medicine and Science in Sports and Exercise, 48(5), 3820-3821. doi: 10.1249/01.mss.0000488223.41775.bc

 

Serum alkalinization and hydrogen-rich water in healthy men ​

“Intake of HRW formulation for 1 week increased fasting and postexercise blood pH in healthy volunteers with no adverse effects reported. Evidence confirmed previous animal studies that suggested that HRW may provide some benefits as a neutralizing agent”

 
Ostojic, S. M. (2012). Serum alkalinization and hydrogen-rich water in healthy men. Mayo Clinic Proceedings, 87(5), 501-502. doi: 10.1016/j.mayocp.2012.02.008

 


Is molecular hydrogen beneficial to enhance post-exercise recovery in female athletes?

“Hydrogen-rich water might be an appropriate and safe hydration strategy that helps athletes to become less susceptible to exercise-induced acidosis.”

Drid, P., Trivic, T., Casals, C., Trivic, S., Stojanovic, M., & Ostojic, S. (2016). Is molecular hydrogen beneficial to enhance post-exercise recovery in female athletes? Science & Sports, 31(4), 207-213. doi: 10.1016/j.scispo.2016.04.010

 

Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women: Double-blind, randomized, placebo-controlled, cross-over trial of efficacy and safety

“Due to the fact that negative oxidation reduction potential exhibits high pH, low dissolved oxygen and extremely high dissolved molecular hydrogen, it seems that increased non-volatile base indicators in the plasma for NORP group arose from ingestion of the alkaline drink. Due to the fact that the intestine is directly involved in acid and/or base generation, it appears that NORP has a strong alkalizing effect as a result of absorption of inorganic cations, while protective mechanisms of NORP results from active atomic hydrogen with high reductive ability. Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women by reducing the rate of blood lactate accumulation during and after exercise, increase time to exhaustion, increase serum buffering capacity and not increase prevalence of adverse effects as compared to the control drink.”

 

Ostojić, S. (2011). Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women: Double-blind, randomized, placebo-controlled, cross-over trial of efficacy and safety. Serbian Journal of Sports Sciences, 5(3), 83-89.

 

Hydrogen-rich water affected blood alkalinity in physically active men

“Intake of HRW significantly increased fasting arterial blood pH by 0.04 (95% confidence interval; 0.01 - 0.08; p < 0.001), and postexercise pH by 0.07 (95% confidence interval; 0.01 - 0.10; p = 0.03) after 14 days of intervention. Fasting bicarbonates were significantly higher in the HRW trial after the administration regimen as compared with the preadministration (30.5 ± 1.9 mEq/L vs. 28.3 ± 2.3 mEq/L; p < 0.0001). No volunteers withdrew before the end of the study, and no participant reported any vexatious side effects of supplementation. These results support the hypothesis that HRW administration is safe and may have an alkalizing effect in young physically active men.”

 

Ostojic, S. M., & Stojanovic, M. D. (2014). Hydrogen-rich water affected blood alkalinity in physically active men. Research in Sports Medicine, 22(1), 49-60. doi: 10.1080/15438627.2013.852092


Selective protective effect of hydrogen water on free radical injury of athletes after high-intensity exercise


“The serum superoxide anions, serum SOD activities, and total antioxidant capacities of athletes during and after training were significantly superior to those of the control group (P<0.05), and the difference was statistically significant. Hydrogen water supplement could effectively reduce the oxidized substances in athletes before, during, and after exercise and could prevent the free radical injury caused by high-intensity exercise.”

Sun, Y., & Sun, L. (217). Selective protective effect of hydrogen water on free radical injury of athletes after high-intensity exercise. Biomedical Research,28(10), 4588-4561. Retrieved from http://www.alliedacademies.org/articles/selective-protective-effect-of-hydrogen-water-on-free-radical-injury-of-athletes-after-highintensity-exercise.html


Effects of hydrogen bathing on exercise-induced oxidative stress and delayed-onset muscle soreness

 

“On the other hand, hydrogen bathing significantly reduced DOMS (VAS) 1 and 2days after downhill running (p=0.033). These findings suggest that hydrogen bath after downhill exercise can be effective for reduction of DOMS.”

Kawamura, T., Gando, Y., Takahashi, M., Hara, R., Suzuki, K., & Muraoka, I. (2016). Effects of hydrogen bathing on exercise-induced oxidative stress and delayed-onset muscle soreness. Japanese Journal of Physical Fitness and Sports Medicine,65(3), 297-305. doi: https://doi.org/10.7600/jspfsm.65.297

Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries

“Oral and topical hydrogen intervention was found to augment plasma viscosity decrease as compared with the control group (P = 0.04). Differences were found for range-of-motion recovery between the 3 groups; oral and topical hydrogen intervention resulted in a faster return to normal joint range of motion for both flexion and extension of the injured limb as compared with the control intervention (P < 0.05). These preliminary results support the hypothesis that the addition of hydrogen to traditional treatment protocols is potentially effective in the treatment of soft tissue injuries in male professional athletes.”

Ostojic, S. M., Vukomanovic, B., Calleja-Gonzalez, J., & Hoffman, J. R. (2014). Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries. Postgraduate Medicine, 126(5), 188-196. doi: 10.3810/pgm.2014.09.2813

 



Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury

“Overall, these studies provide proof of principle that mHW can potently reverse, block, or attenuate many of the effects of CCI. These include effects on edema formation, tau pathology, regulators of fluid and BBB functions, neuroinflammation, and gene expression.”

Dohi, K., Kraemer, B. C., Erickson, M. A., Mcmillan, P. J., Kovac, A., Flachbartova, Z., . . . Banks, W. A. (2014). Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. PLOS ONE, 9(9), 1-16. doi: 10.1371/journal.pone.0108034

Drinking hydrogen water enhances endurance and relieves psychometric fatigue

"Endurance and fatigue were significantly improved in the H2 group as judged by maximal oxygen consumption and Borg's scale, respectively. Taken together, drinking H2 water just before exercise exhibited anti-fatigue and endurance effects."

 

Mikami, T., Tano, K., Lee, H., Lee, H., Park, J., Ohta, F., … Ohta, S. (2019). Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study. Canadian Journal of Physiology and Pharmacology, 97(9), 857–862. doi: 10.1139/cjpp-2019-0059

Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes

“Although acute exercise resulted in an increase in blood lactate levels in the subjects given placebo water, oral intake of hydrogen water prevented an elevation of blood lactate during heavy exercise. Peak torque of placebo water significantly decreased during maximal isokinetic knee extension, suggesting muscle fatigue, but peak torque of hydrogen water didn’t decrease at early phase. Proper and adequate hydration is helpful for elite athletes to achieve the best performance. Hydrogen water can easily replace regular drinking water on a routine basis and would potentially prevent adverse effects associated with heavy exercise. In conclusion, our preliminary data demonstrated that consumption of hydrogen water reduced blood lactate levels and improved muscle fatigue after acute exercise. Drinking hydrogen water would be a novel and effective fluid hydration strategy for athletes.”

 

Aoki, K., Nakao, A., Adachi, T., Matsui, Y., & Miyakawa, S. (2012). Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Medical Gas Research, 2(12), 1-6. doi: 10.1186/2045-9912-2-12

 

 

Effects of hydrogen rich water on prolonged intermittent exercise

 

“In the PLA group, PPO in absolute values decreased significantly at the 8th and 9th of 10 sprints and in relative values, PPO, decrease significantly at 6th, 8th and 9th of 10 sprints (by mean: -12±5%, p<0.006), while it remained unchanged in HRW group. Two weeks of HRW intake may help to maintain PPO in repetitive sprints to exhaustion over 30 minutes.”

 

Ponte, A. D., Giovanelli, N., Nigris, D., & Lazzer, S. (n.d.). Effects of hydrogen rich water on prolonged intermittent exercise. The Journal of sports medicine and physical fitness, 57(6). doi: 10.23736/S0022-4707.17.06883-9



Molecular hydrogen affected post-exercise recovery in judo athletes

“Molecular hydrogen significantly blunted lactate response during recovery period as compared to the placebo (7.23 ± 1.95 vs 9.22 ± 1.51 mmol/L; p = 0.011). Furthermore, a trend has been found for decreased post-exercise heart rate in group supplemented with H2 (p = 0.111). Hydrogen-rich water appears to be an appropriate strategy to positively affect post-exercise lactates in judo athletes.”

Drid, P., Stojanovic, M. D., Trivic, T., & Ostojic, S. M. (2016). Molecular hydrogen affected post-exercise recovery in judo athletes. Medicine and Science in Sports and Exercise, 48(5), 3820-3821. doi: 10.1249/01.mss.0000488223.41775.bc

 

Serum alkalinization and hydrogen-rich water in healthy men ​

“Intake of HRW formulation for 1 week increased fasting and postexercise blood pH in healthy volunteers with no adverse effects reported. Evidence confirmed previous animal studies that suggested that HRW may provide some benefits as a neutralizing agent”

 
Ostojic, S. M. (2012). Serum alkalinization and hydrogen-rich water in healthy men. Mayo Clinic Proceedings, 87(5), 501-502. doi: 10.1016/j.mayocp.2012.02.008

 


Is molecular hydrogen beneficial to enhance post-exercise recovery in female athletes?

“Hydrogen-rich water might be an appropriate and safe hydration strategy that helps athletes to become less susceptible to exercise-induced acidosis.”

Drid, P., Trivic, T., Casals, C., Trivic, S., Stojanovic, M., & Ostojic, S. (2016). Is molecular hydrogen beneficial to enhance post-exercise recovery in female athletes? Science & Sports, 31(4), 207-213. doi: 10.1016/j.scispo.2016.04.010

 

Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women: Double-blind, randomized, placebo-controlled, cross-over trial of efficacy and safety

“Due to the fact that negative oxidation reduction potential exhibits high pH, low dissolved oxygen and extremely high dissolved molecular hydrogen, it seems that increased non-volatile base indicators in the plasma for NORP group arose from ingestion of the alkaline drink. Due to the fact that the intestine is directly involved in acid and/or base generation, it appears that NORP has a strong alkalizing effect as a result of absorption of inorganic cations, while protective mechanisms of NORP results from active atomic hydrogen with high reductive ability. Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women by reducing the rate of blood lactate accumulation during and after exercise, increase time to exhaustion, increase serum buffering capacity and not increase prevalence of adverse effects as compared to the control drink.”

 

Ostojić, S. (2011). Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women: Double-blind, randomized, placebo-controlled, cross-over trial of efficacy and safety. Serbian Journal of Sports Sciences, 5(3), 83-89.

 

Hydrogen-rich water affected blood alkalinity in physically active men

“Intake of HRW significantly increased fasting arterial blood pH by 0.04 (95% confidence interval; 0.01 - 0.08; p < 0.001), and postexercise pH by 0.07 (95% confidence interval; 0.01 - 0.10; p = 0.03) after 14 days of intervention. Fasting bicarbonates were significantly higher in the HRW trial after the administration regimen as compared with the preadministration (30.5 ± 1.9 mEq/L vs. 28.3 ± 2.3 mEq/L; p < 0.0001). No volunteers withdrew before the end of the study, and no participant reported any vexatious side effects of supplementation. These results support the hypothesis that HRW administration is safe and may have an alkalizing effect in young physically active men.”

 

Ostojic, S. M., & Stojanovic, M. D. (2014). Hydrogen-rich water affected blood alkalinity in physically active men. Research in Sports Medicine, 22(1), 49-60. doi: 10.1080/15438627.2013.852092


Selective protective effect of hydrogen water on free radical injury of athletes after high-intensity exercise


“The serum superoxide anions, serum SOD activities, and total antioxidant capacities of athletes during and after training were significantly superior to those of the control group (P<0.05), and the difference was statistically significant. Hydrogen water supplement could effectively reduce the oxidized substances in athletes before, during, and after exercise and could prevent the free radical injury caused by high-intensity exercise.”

Sun, Y., & Sun, L. (217). Selective protective effect of hydrogen water on free radical injury of athletes after high-intensity exercise. Biomedical Research,28(10), 4588-4561. Retrieved from http://www.alliedacademies.org/articles/selective-protective-effect-of-hydrogen-water-on-free-radical-injury-of-athletes-after-highintensity-exercise.html


Effects of hydrogen bathing on exercise-induced oxidative stress and delayed-onset muscle soreness

 

“On the other hand, hydrogen bathing significantly reduced DOMS (VAS) 1 and 2days after downhill running (p=0.033). These findings suggest that hydrogen bath after downhill exercise can be effective for reduction of DOMS.”

Kawamura, T., Gando, Y., Takahashi, M., Hara, R., Suzuki, K., & Muraoka, I. (2016). Effects of hydrogen bathing on exercise-induced oxidative stress and delayed-onset muscle soreness. Japanese Journal of Physical Fitness and Sports Medicine,65(3), 297-305. doi: https://doi.org/10.7600/jspfsm.65.297

Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries

“Oral and topical hydrogen intervention was found to augment plasma viscosity decrease as compared with the control group (P = 0.04). Differences were found for range-of-motion recovery between the 3 groups; oral and topical hydrogen intervention resulted in a faster return to normal joint range of motion for both flexion and extension of the injured limb as compared with the control intervention (P < 0.05). These preliminary results support the hypothesis that the addition of hydrogen to traditional treatment protocols is potentially effective in the treatment of soft tissue injuries in male professional athletes.”

Ostojic, S. M., Vukomanovic, B., Calleja-Gonzalez, J., & Hoffman, J. R. (2014). Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries. Postgraduate Medicine, 126(5), 188-196. doi: 10.3810/pgm.2014.09.2813

 



Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury

“Overall, these studies provide proof of principle that mHW can potently reverse, block, or attenuate many of the effects of CCI. These include effects on edema formation, tau pathology, regulators of fluid and BBB functions, neuroinflammation, and gene expression.”

Dohi, K., Kraemer, B. C., Erickson, M. A., Mcmillan, P. J., Kovac, A., Flachbartova, Z., . . . Banks, W. A. (2014). Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. PLOS ONE, 9(9), 1-16. doi: 10.1371/journal.pone.0108034